Drug Literature

"There are no really 'safe' biologically active drugs. There are only 'safe' physicians."
Harold A. Kaminetzky, 1923- . Obstetrics and Gynecology 1963;21:512.

"We are a bitters-and-pill-taking people."
John Shaw Billings, 1838-1913. Boston Medical and Surgical Journal 1891;124:349

See also Dr. Paul Cuddy's presentation "Evaluating Literature Actively" to learn how to understand and evaluate drug studies in medical journals.

Books

Most pharmacology books are shelved in the QV section of the library. There are many reference books available that will identify drugs and pharmaceuticals from many countries, their chemical properties, their administration and dosage, drug interactions and side effects, pictorial identification charts, directories of pharmaceutical companies and poison control centers,etc. Be sure to ask your librarian if you don't find what you want. Remember also the Drug Information Center in the UMKC School of Medicine.

Reference and Reserve books include (but are not limited to!):

If you don't find what you need, visit (or call or email) your librarian. Remember to ask the librarian also about the Substance Abuse Treatment collection.

Journals

Pharmacology journals are indexed in MEDLINE (and in IPA and TOXNET,etc.), and are shelved alphabetically by title in the Health Sciences Library.

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Databases

MEDLINE

Medline is an index of clinical medical journal literature from 1966 to the present; currently about 3500 journals in 70 languages are indexed. The entire D tree is devoted to chemicals and drugs.

Medline Search Hint

Search MEDLINE by the generic drug name, not the trade name. To search literature published throughout the life of a drug, build a hedge that includes all known names, registry numbers, CAS numbers, etc. Many useful subheadings can be attached to a drug name, such as "antagonists and inhibitors," "chemical synthesis," "chemistry," "contraindications," etc. To search adverse effects of drugs thoroughly, use the subheadings "adverse effects," "poisoning," and "toxicity." There is a subheading "administration and dosage" but remember there are also MeSH terms for drug administration routes. Remember that the subheadings "chemically induced" and "drug therapy" can be attached to MeSH terms for diseases, and "drug effects" can be attached to MeSH terms for organisms, organs, and physiological or psychological processes. There are MeSH terms for drug interactions, drug eruptions, drug resistance, etc. MeSH Supplementary Chemical Records identifies many drugs and chemicals that do not have unique MeSH terms, and maps them to the appropriate MeSH while also listing synonyms and Registry Numbers.

See the Medline Search Tools or consult your librarian for further information. For an introduction to Medline search skills, see the Medline Searching Instruction Guide or consult your librarian.

EMBASE

Abstracts and citations to international literature on drugs, pharmacology, and human medicine, including European and Asian journals not cited in MEDLINE.

International Pharmaceutical Abstracts

Information on all phases of the development and use of drugs and on professional pharmaceutical practice.

TOXNET

Toxnet databases available through the National Library of Medicine include:
CCRIS Chemical Carcinogenesis Research Information System
DART Developmental and Reproductive Toxicology EMIC Environmental Mutagen Information Center GENE-TOX HSDB Hazardous Substances Data Bank IRIS Integrated Risk Information System RTECS Registry of Toxic Effects of Chemical Substances TRI Toxic Chemical Release Inventory

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Images

Remember that slides, CD-ROM images, and other visual information are available in the Medical Education Media Center. See also the University of Missouri-Kansas City Image Bank.

Internet Resources - World Wide Web

CML's Information Resources Home Page UMKC School of Medicine Home Page UMKC Health Sciences Library Home Page


http://research.med.umkc.edu/teams/cml/Druglit.html updated 3/97 by pfannenstiel@cctr.umkc.edu